1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-8-trifluoromethyl-3-quinolinecarboxylic acid → 7-[3-[2-(Aminomethyl)phenyl]-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid
Reaction equation
[CH:1]1([n:4]2[cH:5][c:6]([C:21](=[O:22])[OH:23])[c:7](=[O:20])[c:8]3[cH:9][c:10]([F:19])[c:11]([F:18])[c:12]([C:14]([F:15])([F:16])[F:17])[c:13]23)[CH2:2][CH2:3]1.[NH:24]1[CH2:25][CH:26]([c:29]2[c:30]([CH2:35][NH2:36])[cH:31][cH:32][cH:33][cH:34]2)[CH2:27][CH2:28]1>>[CH:1]1([n:4]2[cH:5][c:6]([C:21](=[O:22])[OH:23])[c:7](=[O:20])[c:8]3[cH:9][c:10]([F:19])[c:11]([N:24]4[CH2:25][CH:26]([c:29]5[c:30]([CH2:35][NH2:36])[cH:31][cH:32][cH:33][cH:34]5)[CH2:27][CH2:28]4)[c:12]([C:14]([F:15])([F:16])[F:17])[c:13]23)[CH2:2][CH2:3]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-62d2d2c28b3544c88c3e5208cabe13d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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