2-Isocyanatopyridine → tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-[4-(pyridin-2-ylcarbamoyloxy)-phenyl]-piperidine-1-carboxylate

HRID 1208590Notes

Reaction equation

HRID 1208590 reaction equation
[OH:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:21][CH2:22][c:23]3[cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[cH:31][cH:32]3)[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[n:33]1[c:34]([N:39]=[C:40]=[O:41])[cH:35][cH:36][cH:37][cH:38]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:21][CH2:22][c:23]3[cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[cH:31][cH:32]3)[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1)[C:40]([NH:39][c:34]1[n:33][cH:38][cH:37][cH:36][cH:35]1)=[O:41]

Participants

3

Reactant 2

HCID 5775672-IsocyanatopyridineHCID 86604423tert-butyl (3RS,4RS)-4-(4-hydroxy-phenyl)-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate

Product 1

HCID 54177591tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-[4-(pyridin-2-ylcarbamoyloxy)-phenyl]-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-fc9afb134b004c7b9ea791d14bf59a44
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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