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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1208870Generated: November 1, 2026

Sodium ion → 2-[5-(4-Methyl-piperazin-1-ylmethyl)-2-nitro-phenylamino]-4-(3-trifluoromethylphenyl)-thiazole-5-carboxylic acid amide

https://huagongshe.com/reaction/1208870

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
Reactant1-MethylpiperazineHCID 53167—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant2-(5-Formyl-2-nitro-phenylamino)-4-(3-trifluoromethyl-phenyl)-thiazole-5-carboxylic acid amideHCID 86642854—
Product2-[5-(4-Methyl-piperazin-1-ylmethyl)-2-nitro-phenylamino]-4-(3-trifluoromethylphenyl)-thiazole-5-carboxylic acid amideHCID 86642855—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-48e3930dcbae4f6aab414267622ab558
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)