Nicotinoyl chloride → 7-Nicotinoyloxy-2-{4-[bis-(4-fluorophenyl)methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxin
Reaction equation
[C:35]([c:36]1[cH:37][n:38][cH:39][cH:40][cH:41]1)(=[O:42])[Cl:43].[OH:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:34]1)[O:7][C:8]([C:11](=[O:12])[N:13]1[CH2:14][CH2:15][N:16]([CH:19]([c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[c:27]3[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]3)[CH2:17][CH2:18]1)=[CH:9][O:10]2>>[O:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:34]1)[O:7][C:8]([C:11](=[O:12])[N:13]1[CH2:14][CH2:15][N:16]([CH:19]([c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[c:27]3[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]3)[CH2:17][CH2:18]1)=[CH:9][O:10]2)[C:35]([c:36]1[cH:37][n:38][cH:39][cH:40][cH:41]1)=[O:42]Participants
3
Sources & evidence
- ORD record
- ord-99216373a03846a1ba661d1bdb590ca8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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