tert-Butyl piperazine-1-carboxylate → 4-(4-tert-butoxycarbonyl-1-piperazinyl)methyl-2-cyclopropylmethyl-6-(2,3-dihydro-1-benzofuran-5-yl)-2H-pyridazin-3-one
Reaction equation
[C:55]([CH3:56])([CH3:57])([CH3:58])[O:59][C:60](=[O:61])[N:62]1[CH2:63][CH2:64][NH:65][CH2:66][CH2:67]1.[CH:1]1([CH2:4][n:5]2[n:6][c:7](-[c:20]3[cH:21][cH:22][c:23]4[c:24]([cH:28]3)[CH2:25][CH2:26][O:27]4)[cH:8][c:9]([CH2:12][N:13]3[CH2:14][CH2:15][N:16]([CH3:17])[CH2:18][CH2:19]3)[c:10]2=[O:11])[CH2:2][CH2:3]1.[CH:29]1([CH2:30][n:31]2[c:32](=[O:33])[c:34]([CH2:35][O:36][S:37]([CH3:38])(=[O:39])=[O:40])[cH:41][c:42](-[c:43]3[cH:44][cH:45][c:46]4[c:50]([cH:51]3)[CH2:49][CH2:48][O:47]4)[n:52]2)[CH2:53][CH2:54]1>>[CH:1]1([CH2:4][n:5]2[n:6][c:7](-[c:20]3[cH:21][cH:22][c:23]4[c:24]([cH:28]3)[CH2:25][CH2:26][O:27]4)[cH:8][c:9]([CH2:12][N:65]3[CH2:64][CH2:63][N:62]([C:60]([O:59][C:55]([CH3:56])([CH3:57])[CH3:58])=[O:61])[CH2:67][CH2:66]3)[c:10]2=[O:11])[CH2:2][CH2:3]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d801c6c4173346a6ae5d341bd46c1585
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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