Methanol → racemic (2'S,3S,4'R)-6-chloro-2'-(3-chlorophenyl)-4'-cyclopentyl spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

HRID 1209384Notes

Reaction equation

HRID 1209384 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[N:6]1[C:7](=[O:34])[C:8]2([c:9]3[cH:10][cH:11][c:12]([Cl:15])[cH:13][c:14]31)[CH:16]([c:27]1[cH:28][c:29]([Cl:33])[cH:30][cH:31][cH:32]1)[NH:17][C:18](=[O:26])[CH2:19][CH:20]2[CH:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1)[CH3:5].[CH3:37][OH:38].[Na+:36].[OH-:35]>>[NH:6]1[C:7](=[O:34])[C:8]2([c:9]3[cH:10][cH:11][c:12]([Cl:15])[cH:13][c:14]31)[CH:16]([c:27]1[cH:28][c:29]([Cl:33])[cH:30][cH:31][cH:32]1)[NH:17][C:18](=[O:26])[CH2:19][CH:20]2[CH:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 90971499racemic (2'S,3S,4'R)-6-chloro-2'-(3-chlorophenyl)-4'-cyclopentyl-2,3-dihydro-2,6'-dioxo spiro[indole-3,3'-piperidine]-1-carboxylic acid ethyl ester

Product 1

HCID 131727307racemic (2'S,3S,4'R)-6-chloro-2'-(3-chlorophenyl)-4'-cyclopentyl spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

Sources & evidence

ORD record
ord-d0d147419156436a8c068b40c83598c5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…