HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1209595Generated: October 30, 2026
2-Methyl-3-butyn-2-ol → 2-Methyl-4-{5-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-but-3-yn-2-ol
https://huagongshe.com/reaction/1209595
Participants
| Role | Name | HCID | Charge |
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| Reactant | 2-Methyl-3-butyn-2-ol | HCID 8258 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Palladium Chloride | HCID 24290 | — |
| Reactant | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Reactant | {4-[5-Bromothiophen-2-yl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine | HCID 57936128 | — |
| Product | 2-Methyl-4-{5-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-but-3-yn-2-ol | HCID 11383972 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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| ORD ID | ord-ffea700a8b564910af5dbc512d5a772d |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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