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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1209674Generated: October 25, 2026

Acetonitrile → 2-[4-[[2-[tert-butyl(dimethyl)silyl]oxy-1-(2-methylpyrimidin-5-yl)ethyl]amino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-chlorobenzonitrile

https://huagongshe.com/reaction/1209674

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Chloro-2-(4-chloro-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)benzonitrileHCID 59840687—
Reactant2-[Tert-butyl(dimethyl)silyl]oxy-1-(2-methylpyrimidin-5-yl)ethanamineHCID 77218293—
Product2-[4-[[2-[tert-butyl(dimethyl)silyl]oxy-1-(2-methylpyrimidin-5-yl)ethyl]amino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-chlorobenzonitrileHCID 69177699—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-7ee270e9c5e84ff9b0a123204ad9a8ae
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)