2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde → 2-[4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-N-methyl-isobutyramide

HRID 1209721Notes

Reaction equation

HRID 1209721 reaction equation
[CH3:19][NH:20][C:21]([C:22]([CH3:23])([CH3:24])[N:25]1[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1)=[O:31].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH:11]=[O:12])[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:28]1[CH2:27][CH2:26][N:25]([C:22]([C:21]([NH:20][CH3:19])=[O:31])([CH3:23])[CH3:24])[CH2:30][CH2:29]1)[s:10]2

Participants

3

Reactant 2

HCID 457899852-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehydeHCID 57512955N-methyl-2-piperazin-1-yl-isobutyramide

Product 1

HCID 574939952-[4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-N-methyl-isobutyramide

Sources & evidence

ORD record
ord-05069635d3bb44828b5d2228639df407
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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