Methanol → Ethyl 5-[3-[2-chloro-4-(trifluoromethyl)phenyl]prop-2-ynoylamino]-2-[2-(diethylamino)ethoxy]benzoate
Reaction equation
[CH3:37][OH:38].[Cl:1][c:2]1[c:3]([C:12]#[C:13][C:14](=[O:15])[OH:16])[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Cl:39][CH2:40][Cl:41].[NH2:17][c:18]1[cH:19][cH:20][c:21]([O:29][CH2:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[c:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:28]1>>[Cl:1][c:2]1[c:3]([C:12]#[C:13][C:14](=[O:16])[NH:17][c:18]2[cH:19][cH:20][c:21]([O:29][CH2:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[c:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:28]2)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-337c71dc7bdc4eeea0f95b1b0cabde49
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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