Methanol → 5-[2-Fluoro-4-(methylthio)phenyl]-2-pyrazinamine
Reaction equation
[Br:13][c:14]1[n:15][cH:16][c:17]([NH2:20])[n:18][cH:19]1.[C:21](=[O:22])([O-:23])[O-:24].[CH2:27]1[O:28][CH2:29][CH2:30][O:31][CH2:32]1.[CH3:114][OH:115].[Cl:110][CH2:111][Cl:112].[F:1][c:2]1[c:3]([B:10]([OH:11])[OH:12])[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1.[Na+:25].[Na+:26].[OH2:113].[cH:33]1[cH:34][cH:35][c:36]([P:37]([Pd:38]([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[cH:108][cH:109]1>>[F:1][c:2]1[c:3](-[c:14]2[n:15][cH:16][c:17]([NH2:20])[n:18][cH:19]2)[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-3d86dd9990f549b6b73773ccdc256b11
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…