Benzenamine, 3-ethynyl- → Ethyl 4-[(3-ethynylphenyl)amino]-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate

HRID 1210028Notes

Reaction equation

HRID 1210028 reaction equation
[C:19](#[CH:20])[c:21]1[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]1[c:10]2[CH2:11][N:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:13]1>>[c:2]1([NH:24][c:23]2[cH:22][c:21]([C:19]#[CH:20])[cH:27][cH:26][cH:25]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]1[c:10]2[CH2:11][N:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:13]1

Participants

3

Reactant 2

HCID 104682Benzenamine, 3-ethynyl-HCID 58116864Ethyl12-chloro-7-thia-4,9,11-triazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9,11-tetraene-4-carboxylate

Product 1

HCID 58116910Ethyl 4-[(3-ethynylphenyl)amino]-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate

Sources & evidence

ORD record
ord-9580120fc80644d1bc5c31feb0a20b8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…