Water → 2-(4-amino-2-butoxy-6-methylpyridin-3-yl)-4-bromo-N,N-diisopropylbenzamide

HRID 1210115Notes

Reaction equation

HRID 1210115 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:11](=[O:12])[N:13]([CH:14]([CH3:15])[CH3:16])[CH:17]([CH3:18])[CH3:19])[c:6]([B:8]([OH:9])[OH:10])[cH:7]1.[C:34](=[O:35])([O-:36])[O-:37].[CH2:20]([CH2:21][CH2:22][CH3:23])[O:24][c:25]1[n:26][c:27]([CH3:33])[cH:28][c:29]([NH2:32])[c:30]1[I:31].[Cs+:38].[Cs+:39].[O:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1.[OH2:46]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:11](=[O:12])[N:13]([CH:14]([CH3:15])[CH3:16])[CH:17]([CH3:18])[CH3:19])[c:6](-[c:30]2[c:25]([O:24][CH2:20][CH2:21][CH2:22][CH3:23])[n:26][c:27]([CH3:33])[cH:28][c:29]2[NH2:32])[cH:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 59375409(5-Bromo-2-(diisopropylcarbamoyl)phenyl)boronic acidHCID 593754672-Butoxy-3-iodo-6-methylpyridin-4-amine

Product 1

HCID 593754382-(4-amino-2-butoxy-6-methylpyridin-3-yl)-4-bromo-N,N-diisopropylbenzamide

Sources & evidence

ORD record
ord-808c865ca95d46f8aa87d943fbd5d540
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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