4-Hydroxyproline → Methyl 1-[(3-chloro-4-cyano-2-methylphenyl)carbamoyl]-3-hydroxypyrrolidine-2-carboxylate
Reaction equation
[CH3:10][O:11][C:12](=[O:13])[CH:14]1[NH:15][CH2:16][CH2:17][CH:18]1[OH:19].[Cl:20][c:21]1[c:22]([C:23]#[N:24])[cH:25][cH:26][c:27]([N:30]=[C:31]=[O:32])[c:28]1[CH3:29].[Cl:33][CH2:34][Cl:35].[NH:1]1[CH2:2][CH:3]([OH:4])[CH2:5][CH:6]1[C:7]([OH:8])=[O:9]>>[CH3:10][O:11][C:12](=[O:13])[CH:14]1[N:15]([C:31]([NH:30][c:27]2[cH:26][cH:25][c:22]([C:23]#[N:24])[c:21]([Cl:20])[c:28]2[CH3:29])=[O:32])[CH2:16][CH2:17][CH:18]1[OH:19]Participants
5
Sources & evidence
- ORD record
- ord-4dec058adf7d488191960d43175d60f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…