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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1210690Generated: October 30, 2026

8-Amino-1-(2-methoxy-ethyl)-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → (2-{5-Chloro-2-[1-(2-methoxy-ethyl)-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino]-pyrimidin-4-ylamino}-3-fluoro-phenoxy)-acetonitrile

https://huagongshe.com/reaction/1210690

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Amino-1-(2-methoxy-ethyl)-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-oneHCID 67264165—
Reactant[2-(2,5-Dichloropyrimidin-4-ylamino)-3-fluorophenoxy]-acetonitrileHCID 86633948—
Product(2-{5-Chloro-2-[1-(2-methoxy-ethyl)-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino]-pyrimidin-4-ylamino}-3-fluoro-phenoxy)-acetonitrileHCID 66830457—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-3ad48d2b21464d8496b5809485d4ce29
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)