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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1210882Generated: November 1, 2026

8-Amino-1-(2-methoxyethyl)-1,3,4,5-tetrahydrobenzo[b]azepin-2-one → 3-Fluoro-2-{2-[1-(2-methoxy-ethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino]-5-trifluoromethyl-pyrimidin-4-ylamino]-N-methyl-benzamide

https://huagongshe.com/reaction/1210882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Amino-1-(2-methoxyethyl)-1,3,4,5-tetrahydrobenzo[b]azepin-2-oneHCID 67263452—
Reactant2-(2-chloro-5-trifluoromethyl-pyrimidin-4-ylamino)-3-fluoro-N-methyl-benzamideHCID 86633945—
Product3-Fluoro-2-{2-[1-(2-methoxy-ethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino]-5-trifluoromethyl-pyrimidin-4-ylamino]-N-methyl-benzamideHCID 66830474—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-5b46b90b042247daa421ae5a5f29fc15
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)