3-Bromopropionitrile → 3-{4-[5-(4-Trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}propionitrile
Reaction equation
[Br:23][CH2:24][CH2:25][C:26]#[N:27].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([N:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[n:13][cH:14]2)[cH:7][cH:8]1)([F:21])[F:22]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([N:15]3[CH2:16][CH2:17][N:18]([CH2:24][CH2:25][C:26]#[N:27])[CH2:19][CH2:20]3)[n:13][cH:14]2)[cH:7][cH:8]1)([F:21])[F:22]Participants
3
Sources & evidence
- ORD record
- ord-20c13fdeaf35402a8c767821eb24c994
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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