Ammonia → N-(3-fluorophenyl)-N-(3,3,3-trifluoro-2-hydroxypropyl)-3-(trifluoromethyl)benzamide

HRID 1211726Notes

Reaction equation

HRID 1211726 reaction equation
[CH3:41][OH:42].[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][c:7]([C:38]([O:8][CH:9]([C:10]([F:11])([F:12])[F:13])[CH2:14][N:15]([C:16]([c:17]2[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]2)=[O:27])[c:28]2[cH:29][c:30]([F:34])[cH:31][cH:32][cH:33]2)=[O:39])[cH:35][cH:36][cH:37]1.[NH3:40]>>[OH:8][CH:9]([C:10]([F:11])([F:12])[F:13])[CH2:14][N:15]([C:16]([c:17]1[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]1)=[O:27])[c:28]1[cH:29][c:30]([F:34])[cH:31][cH:32][cH:33]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 887MethanolHCID 109519142,2,2-Trifluoro-1-[[(3-fluoro-phenyl)[3-(trifluoromethyl)benzoyl]amino]methyl]ethyl 3-trifluoromethyl-benzoate

Product 1

HCID 10949282N-(3-fluorophenyl)-N-(3,3,3-trifluoro-2-hydroxypropyl)-3-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-7727dab2a8f54d9b81124571b87c8292
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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