Acetonitrile → 3-{2-Methyl-4-[4-phenoxymethyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-phenyl}-propionic acid methyl ester
Reaction equation
[C:15](=[O:16])([O-:17])[O-:18].[CH3:1][O:2][C:3]([CH2:4][CH2:5][c:6]1[c:7]([CH3:13])[cH:8][c:9]([SH:12])[cH:10][cH:11]1)=[O:14].[CH3:46][C:47]#[N:48].[Cl:21][CH2:22][c:23]1[c:24]([CH2:38][O:39][c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[n:25][c:26](-[c:28]2[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]2)[s:27]1.[Cs+:19].[Cs+:20]>>[CH3:1][O:2][C:3]([CH2:4][CH2:5][c:6]1[c:7]([CH3:13])[cH:8][c:9]([S:12][CH2:22][c:23]2[c:24]([CH2:38][O:39][c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[n:25][c:26](-[c:28]3[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]3)[s:27]2)[cH:10][cH:11]1)=[O:14]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-75d80a33a73a49c6a595b37f9dfc8552
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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