Potassium Cation → 7-Fluoro-2-(methoxy)-8-(2-oxiranyl)-1,5-naphthyridine

HRID 1211787Notes

Reaction equation

HRID 1211787 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:12][CH:13]([OH:14])[c:15]2[c:16]([F:27])[cH:17][n:18][c:19]3[cH:20][cH:21][c:22]([O:25][CH3:26])[n:23][c:24]23)(=[O:8])=[O:9])[cH:10][cH:11]1.[CH3:34][OH:35].[K+:32].[K+:33].[OH2:36]>>[CH2:12]1[CH:13]([c:15]2[c:16]([F:27])[cH:17][n:18][c:19]3[cH:20][cH:21][c:22]([O:25][CH3:26])[n:23][c:24]23)[O:14]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 19660Carbonate IonHCID 866033622-[3-Fluoro-6-(methoxy)-1,5-naphthyridin-4-yl]-2-hydroxyethyl 4-methylbenzenesulfonate

Product 1

HCID 590032567-Fluoro-2-(methoxy)-8-(2-oxiranyl)-1,5-naphthyridine

Sources & evidence

ORD record
ord-50323ececf5a4ff39b920c319ed1072f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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