HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1211901Generated: October 31, 2026
1,2-Dichloroethane → 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-trimethylsilanylethynylpyrimidine-4-carboxylic acid methyl ester
https://huagongshe.com/reaction/1211901
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Palladium Chloride | HCID 24290 | — |
| Reactant | Trimethyl((tributylstannyl)ethynyl)silane | HCID 639663 | — |
| Reactant | 6-Amino-5-bromo-2-(4-chloro-2-fluoro-3-methoxyphenyl)-pyrimidine-4-carboxylic acid methyl ester | HCID 59432116 | — |
| Product | 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-trimethylsilanylethynylpyrimidine-4-carboxylic acid methyl ester | HCID 59189594 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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| ORD ID | ord-610fb67ba6604cf3a652407c8501143a |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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