Potassium Cation → 4-(2-Carboxyindol-5-yloxy)-6-methoxy-7-(3-piperidinopropoxy)quinazoline

HRID 1211975Notes

Reaction equation

HRID 1211975 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[K+:28].[K+:29].[OH:30][c:31]1[cH:32][c:33]2[cH:34][c:35]([C:40](=[O:41])[OH:42])[nH:36][c:37]2[cH:38][cH:39]1>>[c:2]1([O:30][c:31]2[cH:32][c:33]3[cH:34][c:35]([C:40](=[O:41])[OH:42])[nH:36][c:37]3[cH:38][cH:39]2)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 889585-Hydroxyindole-2-carboxylic acidHCID 110021914-Chloro-6-methoxy-7-(3-(piperidin-1-YL)propoxy)quinazoline

Product 1

HCID 220307904-(2-Carboxyindol-5-yloxy)-6-methoxy-7-(3-piperidinopropoxy)quinazoline

Sources & evidence

ORD record
ord-a10c3bcb9f234c63a45c5da738ebf5ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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