Dichloromethane → 1-(4-chloro-3-trifluoromethyl-phenyl)-3-[3-(3-pyridin-4-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]thiazin-2-yl)-phenyl]-urea

HRID 1212163Notes

Reaction equation

HRID 1212163 reaction equation
[Cl:23][c:24]1[c:25]([C:33]([F:34])([F:35])[F:36])[cH:26][c:27]([N:30]=[C:31]=[O:32])[cH:28][cH:29]1.[Cl:37][CH2:38][Cl:39].[n:1]1[cH:2][cH:3][c:4](-[c:7]2[c:8](-[c:16]3[cH:17][c:18]([NH2:22])[cH:19][cH:20][cH:21]3)[n:9][n:10]3[c:11]2[S:12][CH2:13][CH2:14][CH2:15]3)[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4](-[c:7]2[c:8](-[c:16]3[cH:17][c:18]([NH:22][C:31]([NH:30][c:27]4[cH:26][c:25]([C:33]([F:34])([F:35])[F:36])[c:24]([Cl:23])[cH:29][cH:28]4)=[O:32])[cH:19][cH:20][cH:21]3)[n:9][n:10]3[c:11]2[S:12][CH2:13][CH2:14][CH2:15]3)[cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 674228643-(3-Pyridin-4-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]thiazin-2-yl)-phenylamine

Product 1

HCID 584770911-(4-chloro-3-trifluoromethyl-phenyl)-3-[3-(3-pyridin-4-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]thiazin-2-yl)-phenyl]-urea

Sources & evidence

ORD record
ord-81c423b21db94d6abde3588f0eeb22aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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