6-Chloro-4-(piperidin-4-ylamino)chromen-2-one → 6-Chloro-4-{1-[5-(4-fluoro-phenyl)-5-oxo-pentyl]-piperidin-4-ylamino}-chromen-2-One

HRID 1212285Notes

Reaction equation

HRID 1212285 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:5]([NH:13][CH:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[cH:6][c:7](=[O:12])[o:8][c:9]2[cH:10][cH:11]1.[F:20][c:21]1[cH:22][cH:23][c:24]([C:27]([CH2:28][CH2:29][CH2:30][CH2:31][Cl:32])=[O:33])[cH:25][cH:26]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([NH:13][CH:14]3[CH2:15][CH2:16][N:17]([CH2:31][CH2:30][CH2:29][CH2:28][C:27]([c:24]4[cH:23][cH:22][c:21]([F:20])[cH:26][cH:25]4)=[O:33])[CH2:18][CH2:19]3)[cH:6][c:7](=[O:12])[o:8][c:9]2[cH:10][cH:11]1

Participants

3

Reactant 2

HCID 116376956-Chloro-4-(piperidin-4-ylamino)chromen-2-oneHCID 126497945-Chloro-1-(4-fluorophenyl)-1-oxopentane

Product 1

HCID 208178426-Chloro-4-{1-[5-(4-fluoro-phenyl)-5-oxo-pentyl]-piperidin-4-ylamino}-chromen-2-One

Sources & evidence

ORD record
ord-d76efe7b2f254847b46df3bc485f83c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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