2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → 2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid[6-(3,3-Difluoroazetidin-1-yl)pyridin-3-yl]amide
Reaction equation
[NH2:19][c:20]1[cH:21][n:22][c:23]([N:26]2[CH2:27][C:28]([F:30])([F:31])[CH2:29]2)[cH:24][cH:25]1.[c:1]1(-[c:7]2[o:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]([C:12](=[O:13])[OH:14])[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[o:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]([C:12](=[O:14])[NH:19][c:20]3[cH:21][n:22][c:23]([N:26]4[CH2:27][C:28]([F:30])([F:31])[CH2:29]4)[cH:24][cH:25]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-525754ebaa8c457c9cb9f914cf17f5cc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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