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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1212849Generated: October 27, 2026

2-(Bromomethyl)-5-(trifluoromethyl)furan → 6-fluoro-2'-oxo-1'-[[3-(trifluoromethyl)pyridin-2-yl]methyl]spiro[2H-1-benzofuran-3,3'-indole]-5-carbonitrile

https://huagongshe.com/reaction/1212849

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-5-(trifluoromethyl)furanHCID 2794605—
Reactant2-(Chloromethyl)-3-(trifluoromethyl)pyridineHCID 18361737—
Reactant6-Fluoro-2'-oxo-1,2'-dihydrospiro[1-benzofuran-3,3'-indole]-5-carbonitrileHCID 59352271—
Reactant3-methylspiro[furo[3,2-f][1,2]benzisoxazole-5,3'-indol]-2'(1H)-oneHCID 59352453—
Product6-fluoro-2'-oxo-1'-[[3-(trifluoromethyl)pyridin-2-yl]methyl]spiro[2H-1-benzofuran-3,3'-indole]-5-carbonitrileHCID 59352188—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-aeeafea4e9144008a991075d0efee7a4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)