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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 121295Generated: October 26, 2026

Hydrochloric Acid → 4-fluoro-N-{(1RS,2SR)-2-hydroxy-2-(4-phenoxyphenyl)-1-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]ethyl}-1-naphthamide

https://huagongshe.com/reaction/121295

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant4-Fluoro-1-naphthoic acidHCID 68448—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant(1RS,2SR)-2-amino-1-(4-(phenyloxy)phenyl)-3-(3-((1,1,2,2-tetrafluoroethyl)oxy)phenyl)-1-propanolHCID 22261513—
Product4-fluoro-N-{(1RS,2SR)-2-hydroxy-2-(4-phenoxyphenyl)-1-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]ethyl}-1-naphthamideHCID 22261874—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-689370a84e1949b3a8f3ce06f879cb1b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)