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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1213353Generated: October 26, 2026

Water → 7'-(2-cyclopropylethynyl)-3'-(2-fluoro-2-methylpropoxy)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-2-amine

https://huagongshe.com/reaction/1213353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylamineHCID 7912—
ReactantEthyl AcetateHCID 8857—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantCopper iodideHCID 83717—
ReactantCyclopropylacetyleneHCID 138823—
Reactant7'-bromo-3'-(2-fluoro-2-methylpropoxy)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-2-amineHCID 67241789—
ReactantHCID 178420554HCID 178420554—
Product7'-(2-cyclopropylethynyl)-3'-(2-fluoro-2-methylpropoxy)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-2-amineHCID 67241867—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-7350f3b3887446868f53c673912d4b23
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)