5-(1-hydroxy-2-aminoethyl)-1H-indole-7-carboxamide → 5-[2-({1-[4-({[4-(Acetylamino)phenyl]sulfonyl}amino)phenyl]-4-piperidinyl}amino)-1-hydroxyethyl]-1H-indole-7-carboxamide

HRID 121363Notes

Reaction equation

HRID 121363 reaction equation
[NH2:28][CH2:29][CH:30]([OH:31])[c:32]1[cH:33][c:34]2[cH:35][cH:36][nH:37][c:38]2[c:39]([C:41](=[O:42])[NH2:43])[cH:40]1.[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][c:11]([NH:14][S:15](=[O:16])(=[O:17])[c:18]3[cH:19][cH:20][c:21]([NH:24][C:25]([CH3:26])=[O:27])[cH:22][cH:23]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1>>[CH:2]1([NH:28][CH2:29][CH:30]([OH:31])[c:32]2[cH:33][c:34]3[cH:35][cH:36][nH:37][c:38]3[c:39]([C:41](=[O:42])[NH2:43])[cH:40]2)[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][c:11]([NH:14][S:15](=[O:16])(=[O:17])[c:18]3[cH:19][cH:20][c:21]([NH:24][C:25]([CH3:26])=[O:27])[cH:22][cH:23]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 1279335-(1-hydroxy-2-aminoethyl)-1H-indole-7-carboxamideHCID 22220411N-{4-[4-(4-Oxo-piperidin-1-yl)-phenylsulfamoyl]-phenyl}-acetamide

Product 1

HCID 222202395-[2-({1-[4-({[4-(Acetylamino)phenyl]sulfonyl}amino)phenyl]-4-piperidinyl}amino)-1-hydroxyethyl]-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-c686eb7a9312405a9eb9937d79c7a745
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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