tert-Butyl 4-oxopiperidine-1-carboxylate → Tert-butyl 4-hydroxy-4-(3-methyl-4-phenylphenyl)piperidine-1-carboxylate

HRID 121364Notes

Reaction equation

HRID 121364 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:14])[c:5](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1.[O:15]=[C:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]1>>[c:2]1([C:16]2([OH:15])[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]2)[cH:3][c:4]([CH3:14])[c:5](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 99648454-Bromo-2-methylbiphenyl

Product 1

HCID 18379492Tert-butyl 4-hydroxy-4-(3-methyl-4-phenylphenyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-1aa6b518e66d4a96b49e57b34c234b00
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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