2-Bromoacetamide → 2-(4-{4-[5-(1H-Pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino]phenyl}piperidin-1-yl)acetamide

HRID 1213814Notes

Reaction equation

HRID 1213814 reaction equation
[Br:31][CH2:32][C:33](=[O:34])[NH2:35].[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([c:10]2[cH:11][cH:12][c:13]([NH:16][c:17]3[c:18]4[n:19]([c:20](-[c:23]5[cH:24][n:25][nH:26][cH:27]5)[cH:21][n:22]3)[cH:28][cH:29][n:30]4)[cH:14][cH:15]2)[CH2:8][CH2:9]1>>[N:4]1([CH2:32][C:33](=[O:34])[NH2:35])[CH2:5][CH2:6][CH:7]([c:10]2[cH:11][cH:12][c:13]([NH:16][c:17]3[c:18]4[n:19]([c:20](-[c:23]5[cH:24][nH:25][n:26][cH:27]5)[cH:21][n:22]3)[cH:28][cH:29][n:30]4)[cH:14][cH:15]2)[CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 696322-BromoacetamideHCID 59023097[4-(1-Isopropylpiperidin-4-yl)phenyl]-[5-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amine

Product 1

HCID 590230192-(4-{4-[5-(1H-Pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino]phenyl}piperidin-1-yl)acetamide

Sources & evidence

ORD record
ord-9e835f53ddaf4e2a9bb0230bff10d358
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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