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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 121441Generated: October 27, 2026

Dichloromethane → 6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-1-methyl-4-(3-((trimethylsilyl)ethynyl)phenyl)-1,8-naphthyridin-2(1H)-one

https://huagongshe.com/reaction/121441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Bromo-1-methyl-1H-imidazoleHCID 1515258—
Reactant6-(4-chlorobenzoyl)-1-methyl-4-(3-((trimethylsilyl)ethynyl)phenyl)-1,8-naphthyridin-2(1H)-oneHCID 67428830—
Product6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-1-methyl-4-(3-((trimethylsilyl)ethynyl)phenyl)-1,8-naphthyridin-2(1H)-oneHCID 59334757—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-e87fff86c71c4af191e70d37a3901755
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)