1-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-phenethyloxy-ethanol → N-(1-{4'-[4-(1-Hydroxy-2-phenethyloxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarbonyl)-methanesulfonamide

HRID 1214792Notes

Reaction equation

HRID 1214792 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH:14]([CH2:15][O:16][CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[OH:25])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1.[CH3:26][C:27]1([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32][B:33]([c:34]2[cH:35][cH:36][c:37]([C:40]3([C:43](=[O:44])[NH:45][S:46](=[O:47])(=[O:48])[CH3:49])[CH2:41][CH2:42]3)[cH:38][cH:39]2)[O:50]1>>[c:2]1(-[c:34]2[cH:35][cH:36][c:37]([C:40]3([C:43](=[O:44])[NH:45][S:46](=[O:47])(=[O:48])[CH3:49])[CH2:41][CH2:42]3)[cH:38][cH:39]2)[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH:14]([CH2:15][O:16][CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[OH:25])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 665772101-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-phenethyloxy-ethanolHCID 66577823N-{1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropanecarbonyl}-methanesulfonamide

Product 1

HCID 51352132N-(1-{4'-[4-(1-Hydroxy-2-phenethyloxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarbonyl)-methanesulfonamide

Sources & evidence

ORD record
ord-2f5a5ff70a794eb499765385ff86c0b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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