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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1215018Generated: November 1, 2026

Sodium ion → 2-Chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile

https://huagongshe.com/reaction/1215018

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
Reactant2-Chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrileHCID 57926113—
Reactant1-(3-Bromo-5-Fluoro-pyridin-4-yl)-ethanolHCID 69937909—
Product2-Chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrileHCID 71087596—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-765c912c49654ef8b0af29b306ac2787
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)