1H-Benzimidazole, 2,7-dichloro-5-(trifluoromethyl)- → (2-{4-[7-Chloro-5-(trifluoromethyl)-1H-benzimidazol-2-yl]piperazin-1-yl}pyridin-3-yl)methanol

HRID 1215021Notes

Reaction equation

HRID 1215021 reaction equation
[Cl:15][c:16]1[n:17][c:18]2[c:19]([nH:20]1)[cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][c:24]2[Cl:25].[N:1]1([c:7]2[n:8][cH:9][cH:10][cH:11][c:12]2[CH2:13][OH:14])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[n:8][cH:9][cH:10][cH:11][c:12]2[CH2:13][OH:14])[CH2:2][CH2:3][N:4]([c:16]2[nH:17][c:18]3[c:19]([n:20]2)[cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][c:24]3[Cl:25])[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 669373361H-Benzimidazole, 2,7-dichloro-5-(trifluoromethyl)-HCID 674004062-(1-piperazinyl)-3-Pyridinemethanol

Product 1

HCID 178519687(2-{4-[7-Chloro-5-(trifluoromethyl)-1H-benzimidazol-2-yl]piperazin-1-yl}pyridin-3-yl)methanol

Sources & evidence

ORD record
ord-45c67add5d4546d1a33afb5ab73bb150
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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