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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1215166Generated: October 27, 2026

Tetrahydrofuran → 4-(4-Imino-2-thioxo-1-(4-methylphenyl)-1,3-diazaspiro[4.5]dec-3-yl)-2-trifluoromethylbenzonitrile

https://huagongshe.com/reaction/1215166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant4-Isothiocyanato-2-(trifluoromethyl)benzonitrileHCID 11615540—
Reactant1-p-TolylaminocyclohexanecarbonitrileHCID 59839099—
Product4-(4-Imino-2-thioxo-1-(4-methylphenyl)-1,3-diazaspiro[4.5]dec-3-yl)-2-trifluoromethylbenzonitrileHCID 86609854—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-5a5a7d73426746fba934a82a06560e5d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)