1-Butanol → furan-2-carboxylic acid N'-{2-amino-7-[2-(t-butyldimethylsilanyloxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-hydrazide

HRID 1215167Notes

Reaction equation

HRID 1215167 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][n:9]1[cH:10][cH:11][c:12]2[c:13]1[n:14][c:15]([NH2:19])[n:16][c:17]2[Cl:18])([CH3:20])[CH3:21].[CH2:31]([OH:32])[CH2:33][CH2:34][CH3:35].[o:22]1[c:23]([C:27](=[O:28])[NH:29][NH2:30])[cH:24][cH:25][cH:26]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][n:9]1[cH:10][cH:11][c:12]2[c:13]1[n:14][c:15]([NH2:19])[n:16][c:17]2[NH:30][NH:29][C:27]([c:23]1[o:22][cH:26][cH:25][cH:24]1)=[O:28])([CH3:20])[CH3:21]

Participants

4

Reactant 3

HCID 2631-ButanolHCID 187312-Furancarboxylic acid, hydrazideHCID 866234637-[2-(t-butyldimethylsilanyloxy)ethyl]-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Product 1

HCID 68414130furan-2-carboxylic acid N'-{2-amino-7-[2-(t-butyldimethylsilanyloxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-hydrazide

Sources & evidence

ORD record
ord-5fa85a0264134f758fcb5ecbfbf2eea7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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