4-Chloro-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine → 4-(2-Ethylsulfonyl-5-hydroxyanilino)-2-(2-pyridinyl)-6-trifluoromethylpyrimidine
Reaction equation
[CH2:18]([CH3:19])[S:20](=[O:21])(=[O:22])[c:23]1[c:24]([NH2:25])[cH:26][c:27]([OH:30])[cH:28][cH:29]1.[Cl:1][c:2]1[n:3][c:4](-[c:12]2[n:13][cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[c:2]1([NH:25][c:24]2[c:23]([S:20]([CH2:18][CH3:19])(=[O:21])=[O:22])[cH:29][cH:28][c:27]([OH:30])[cH:26]2)[n:3][c:4](-[c:12]2[n:13][cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-44089ca920024f1eb6c16f377f1d9e2a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…