1-Hydroxybenzotriazole → tert-butyl 3-[3-ethoxy-4-[[5-ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbonyl]amino]piperidin-1-yl]benzoate
Reaction equation
[CH2:24]([CH3:25])[c:26]1[c:27]([C:34]([F:35])([F:36])[F:37])[n:28][c:29]([C:31](=[O:32])[OH:33])[nH:30]1.[NH2:1][CH:2]1[CH:3]([O:21][CH2:22][CH3:23])[CH2:4][N:5]([c:8]2[cH:9][c:10]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:18][cH:19][cH:20]2)[CH2:6][CH2:7]1.[OH:38][n:39]1[c:40]2[c:41]([cH:42][cH:43][cH:44][cH:45]2)[n:46][n:47]1>>[NH:1]([CH:2]1[CH:3]([O:21][CH2:22][CH3:23])[CH2:4][N:5]([c:8]2[cH:9][c:10]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:18][cH:19][cH:20]2)[CH2:6][CH2:7]1)[C:31]([c:29]1[n:28][c:27]([C:34]([F:35])([F:36])[F:37])[c:26]([CH2:24][CH3:25])[nH:30]1)=[O:32]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-836109ed74c44f2497620cbff15478dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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