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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1215468Generated: October 25, 2026

Dimethyl Sulfoxide → Tert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-[1-(3-chloro-4-cyano-2-methylanilino)ethyl]pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/1215468

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantTolueneHCID 1140—
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
ReactantDibenzylidene acetoneHCID 95417—
ReactantCesium cationHCID 104967—
Reactant2-Chloro-4-iodo-3-methylbenzonitrileHCID 16731995—
ReactantHCID 178463372HCID 178463372—
ProductTert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-[1-(3-chloro-4-cyano-2-methylanilino)ethyl]pyrrolidine-1-carboxylateHCID 66878996—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-defca67b79654ff0899117d376dec0c0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)