Methanol → (3-(Piperazin-1-yl)azetidin-1-yl)(6-(trifluoromethyl)benzo[b]thiophen-2-yl)methanone

HRID 1215709Notes

Reaction equation

HRID 1215709 reaction equation
[CH3:32][OH:33].[F:1][C:2]([F:3])([F:4])[C:30]([N:5]1[CH2:6][CH2:7][N:8]([CH:11]2[CH2:12][N:13]([C:15](=[O:16])[c:17]3[cH:18][c:19]4[c:20]([s:21]3)[cH:22][c:23]([C:26]([F:27])([F:28])[F:29])[cH:24][cH:25]4)[CH2:14]2)[CH2:9][CH2:10]1)=[O:31]>>[NH:5]1[CH2:6][CH2:7][N:8]([CH:11]2[CH2:12][N:13]([C:15](=[O:16])[c:17]3[cH:18][c:19]4[c:20]([s:21]3)[cH:22][c:23]([C:26]([F:27])([F:28])[F:29])[cH:24][cH:25]4)[CH2:14]2)[CH2:9][CH2:10]1

Participants

3

Reactant 2

HCID 887MethanolHCID 866492442,2,2-Trifluoro-1-(4-(1-(6-(trifluoromethyl)benzo[b]thiophene-2-carbonyl)azetidin-3-yl)piperazin-1-yl)ethanone

Product 1

HCID 66770300(3-(Piperazin-1-yl)azetidin-1-yl)(6-(trifluoromethyl)benzo[b]thiophen-2-yl)methanone

Sources & evidence

ORD record
ord-070abd7c94ff47ec8fee4516a8bac70f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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