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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1215770Generated: November 2, 2026

1,2-Dichloroethane → 2-amino-N-[cyclobutyl-(3-fluorophenyl)methyl]-8-fluoro-3-methyl-1-oxoisoquinoline-4-carboxamide

https://huagongshe.com/reaction/1215770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantBenzeneHCID 241—
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-Butyl carbazateHCID 70091—
Reactanttert-butyl N-[4-[[cyclobutyl-(3-fluorophenyl)methyl]carbamoyl]-8-fluoro-3-methyl-1-oxoisoquinolin-2-yl]carbamateHCID 67297921—
Reactant2-[1-[[Cyclobutyl-(3-fluorophenyl)methyl]amino]-1,3-dioxobutan-2-yl]-6-fluorobenzoic acidHCID 87234526—
Product2-amino-N-[cyclobutyl-(3-fluorophenyl)methyl]-8-fluoro-3-methyl-1-oxoisoquinoline-4-carboxamideHCID 72262220—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-9cc7f4f446d149a7b0e59cc9e3b5f31b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)