Ethanol → {3-[3-(Azetidin-1-yl)-1,2,4-oxadiazol-5-yl]-5-(4-ethylphenyl)piperidin-1-yl}(4-hydroxypiperidin-1-yl)methanone

HRID 1215906Notes

Reaction equation

HRID 1215906 reaction equation
[CH2:30]1[CH2:31][NH:32][CH2:33]1.[CH3:34][CH2:35][OH:36].[Cl:1][c:2]1[n:3][o:4][c:5]([CH:7]2[CH2:8][N:9]([C:21](=[O:22])[N:23]3[CH2:24][CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]3)[CH2:10][CH:11]([c:13]3[cH:14][cH:15][c:16]([CH2:19][CH3:20])[cH:17][cH:18]3)[CH2:12]2)[n:6]1>>[c:2]1([N:32]2[CH2:31][CH2:30][CH2:33]2)[n:3][o:4][c:5]([CH:7]2[CH2:8][N:9]([C:21](=[O:22])[N:23]3[CH2:24][CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]3)[CH2:10][CH:11]([c:13]3[cH:14][cH:15][c:16]([CH2:19][CH3:20])[cH:17][cH:18]3)[CH2:12]2)[n:6]1

Participants

4

Reactant 3

HCID 702EthanolHCID 10422AzetidineHCID 58116548[3-(3-Chloro-1,2,4-oxadiazol-5-yl)-5-(4-ethylphenyl)piperidin-1-yl](4-hydroxypiperidin-1-yl)-methanone

Product 1

HCID 49819562{3-[3-(Azetidin-1-yl)-1,2,4-oxadiazol-5-yl]-5-(4-ethylphenyl)piperidin-1-yl}(4-hydroxypiperidin-1-yl)methanone

Sources & evidence

ORD record
ord-3983ca7c04464c19bcd31e23b09868d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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