3,5-Bis(trifluoromethyl)benzyl bromide → 3-[3,5-Bis(trifluoromethyl)benzyl]-5-[5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]-1,3-oxazolidin-2-one
Reaction equation
[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([O:26][CH3:27])[c:8](-[c:10]2[c:11]([CH:20]3[CH2:21][NH:22][C:23](=[O:25])[O:24]3)[cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[cH:9]1.[F:28][C:29]([c:30]1[cH:31][c:32]([CH2:33][Br:34])[cH:35][c:36]([C:38]([F:39])([F:40])[F:41])[cH:37]1)([F:42])[F:43]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([O:26][CH3:27])[c:8](-[c:10]2[c:11]([CH:20]3[CH2:21][N:22]([CH2:33][c:32]4[cH:31][c:30]([C:29]([F:28])([F:42])[F:43])[cH:37][c:36]([C:38]([F:39])([F:40])[F:41])[cH:35]4)[C:23](=[O:25])[O:24]3)[cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[cH:9]1Participants
3
Sources & evidence
- ORD record
- ord-84a44f90f2484779b3c8a1d1afe043db
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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