Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate → tert-butyl 4-[4-fluoro-3-(methoxycarbonyl)phenyl]-3,6-dihydropyridine-1(2H)-carboxylate

HRID 121623Notes

Reaction equation

HRID 121623 reaction equation
[Br:23][c:24]1[cH:25][cH:26][c:27]([F:34])[c:28]([C:29](=[O:30])[O:31][CH3:32])[cH:33]1.[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([C:9]2=[CH:14][CH2:13][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:11][CH2:10]2)[O:22]1>>[C:9]1([c:24]2[cH:25][cH:26][c:27]([F:34])[c:28]([C:29](=[O:30])[O:31][CH3:32])[cH:33]2)=[CH:14][CH2:13][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 4642098Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylateHCID 21525435Methyl 5-bromo-2-fluorobenzoate

Product 1

HCID 57880514tert-butyl 4-[4-fluoro-3-(methoxycarbonyl)phenyl]-3,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-2539ff03dddf460cb16d0b5cca162190
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…