2-Bromo-5-(trifluoromethyl)pyridine → N-(4-chloro-3-(5-(trifluoromethyl)pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide
Reaction equation
[Cl:1][c:2]1[c:3]([B:22]2[O:23][C:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[O:30]2)[cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:20])[n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)=[O:21])[cH:6][cH:7]1.[F:31][C:32]([c:33]1[cH:34][cH:35][c:36]([Br:39])[n:37][cH:38]1)([F:40])[F:41]>>[Cl:1][c:2]1[c:3](-[c:36]2[cH:35][cH:34][c:33]([C:32]([F:31])([F:40])[F:41])[cH:38][n:37]2)[cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:20])[n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)=[O:21])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-91a2e8e44bcf44efab7a0dae7ac0e79f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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