1-(diphenylmethyl)-3-[2-hydroxy-4-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-indol-2-one → 1-(diphenylmethyl)-3-(hydroxymethyl)-3-[2-hydroxy-4-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:6][c:7]2[c:8]1[CH:9]([c:10]1[c:11]([OH:12])[cH:13][c:14]3[c:19]([cH:20]1)[O:18][CH2:17][O:15]3)[C:5](=[O:16])[N:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].[c:27]1([CH:33]([N:34]2[C:35](=[O:55])[CH:36]([c:43]3[c:44]([OH:54])[cH:45][c:46]([O:49][C:50]([F:51])([F:52])[F:53])[cH:47][cH:48]3)[c:37]3[cH:38][cH:39][cH:40][cH:41][c:42]32)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[CH2:5]([OH:16])[C:36]1([c:43]2[c:44]([OH:54])[cH:45][c:46]([O:49][C:50]([F:51])([F:52])[F:53])[cH:47][cH:48]2)[C:35](=[O:55])[N:34]([CH:33]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:42]2[c:37]1[cH:38][cH:39][cH:40][cH:41]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e1c299962dba46168e8844a02c1547e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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