Acetate → Ethyl 2-[[1-[2-(6-cyano-3-oxo-1,4-benzoxazin-4-yl)ethyl]piperidin-4-yl]-[3-(2,5-difluorophenyl)prop-2-enyl]amino]acetate
Reaction equation
[C:45]([O-:46])(=[O:47])[CH3:48].[C:50]([O-:51])(=[O:52])[CH3:53].[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[c:3]([CH:9]=[CH:10][CH2:11][NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH2:20][N:21]3[C:22](=[O:33])[CH2:23][O:24][c:25]4[c:26]3[cH:27][c:28]([C:31]#[N:32])[cH:29][cH:30]4)[CH2:17][CH2:18]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[N+:34](=[N-:35])=[CH:36][C:37](=[O:38])[O:39][CH2:40][CH3:41].[Rh+2:49]>>[F:1][c:2]1[c:3]([CH:9]=[CH:10][CH2:11][N:12]([CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH2:20][N:21]3[C:22](=[O:33])[CH2:23][O:24][c:25]4[c:26]3[cH:27][c:28]([C:31]#[N:32])[cH:29][cH:30]4)[CH2:17][CH2:18]2)[CH2:36][C:37](=[O:38])[O:39][CH2:40][CH3:41])[cH:4][c:5]([F:8])[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fa4f82183f0141a48a620d1bb3d0d8ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…