3,5-Dichloro-3-(2-methoxyphenyl)indolin-2-one → 1-[5-chloro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-N-ethyl-4-fluoropyrrolidine-2-carboxamide
Reaction equation
[CH2:21]([CH3:22])[NH:23][C:24]([CH:25]1[NH:26][CH2:27][CH:28]([F:30])[CH2:29]1)=[O:31].[Cl:1][C:2]1([c:13]2[c:14]([O:19][CH3:20])[cH:15][cH:16][cH:17][cH:18]2)[C:3](=[O:12])[NH:4][c:5]2[cH:6][cH:7][c:8]([Cl:11])[cH:9][c:10]21>>[C:2]1([c:13]2[c:14]([O:19][CH3:20])[cH:15][cH:16][cH:17][cH:18]2)([N:26]2[CH:25]([C:24]([NH:23][CH2:21][CH3:22])=[O:31])[CH2:29][CH:28]([F:30])[CH2:27]2)[C:3](=[O:12])[NH:4][c:5]2[cH:6][cH:7][c:8]([Cl:11])[cH:9][c:10]21Participants
3
Sources & evidence
- ORD record
- ord-012fa44f980b437282c4fb84f5159826
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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