Methanol → N-(4-Phenylpiperidin-4-yl)acetamide

HRID 121681Notes

Reaction equation

HRID 121681 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)([NH:20][C:21]([CH3:22])=[O:23])[CH2:12][CH2:13]1.[CH3:24][OH:25].[OH-:26].[OH-:28].[Pd+2:27]>>[NH:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)([NH:20][C:21]([CH3:22])=[O:23])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 18964199N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide

Product 1

HCID 15886675N-(4-Phenylpiperidin-4-yl)acetamide

Sources & evidence

ORD record
ord-e00732326b3f4473b00efb59efeece76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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